Das Problem ist das wenn PGD2 blockiert wird die Stammzellen erst wieder Signale bekommen müssen.
Diese erhalten Sie über die Fettvorläufer in der Kopfhaut. Nimmt die Fetschicht ab nehmen die Haare ab und umgekehrt. Eine Entscheidente Rolle haben die WTN Signale. Diese werden durch DKK-1 überaktivität gehemmt. DKK-1 überaktivität kommt vom TNF Alfa und DHT. Zudem haben die meisten Leute einen B12 Mangel welcher ein WTN Signal aktivator ist. Das kann man erkennen an einem erhöhten HomoCysteinwert. Wen man zu viel B12 hat (sehr selten) umbedingt Fölsäure nehmen.

To understand how significant this PGD2 discovery is, we need to go back to 2001 and remember this study:
Male Pattern Balding May Be Due to Stem Cell Inactivation, According to Penn Study
What the scientists have found is that the bald subjects had the same number of stem cells in their scalp as non-balding subjects.

Using cell samples from men undergoing hair transplants, the team compared follicles from bald scalp and non-bald scalp, and found that bald areas had the same number of stem cells as normal scalp in the same person.

The study was hopeful because if the stem cells were destroyed during the balding process, then reversing baldness would be very difficult. They did, however, find that the progenitor cells in a balding scalp were significantly depleted, and that implies that there is a problem with the activation of stem cells converting to progenitor cells. This may also suggest that there exists an inhibitor that prevents stem cells from being activated.

Fast forward to 2012, if that inhibitor is in fact PGD2(very likely), then removing it would allow follicle stem cells to operate normally and start growing hair. In theory, blocking PGD2 activity would completely reverse balding.

Das PGD2 muss man auch nicht blocken wen man sein Glutathoin level wieder im normall Berreich hat. Siehe dazu nach NRF2 Pathway