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Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness [Beitrag #343215] :: Mo., 17 August 2015 10:47

Ein kurzes "Review", in dem der aktuelle Stand bzgl. Prostaglandine und AGA zusammengefasst ist.
Das Paper wurde von der gleichen Arbeitsgruppe verfasst, die 2012 auch die PGD2-Studie veröffentlicht hatte.

http://europepmc.org/articles/pmc3982925
http://onlinelibrary.wiley.com/doi/10.1111/exd.12348/pdf

Abstract:
Lipids in the skin are the most diverse in the entire human body. Their bioactivity in health and disease is underexplored. Prostaglandin D2 has recently been identified as a factor which is elevated in the bald scalp of men with androgenetic alopecia (AGA) and has the capacity to decrease hair lengthening. An enzyme which synthesizes it, prostaglandin D2 synthase (PTGDS or lipocalin-PGDS), is hormone responsive in multiple other organs. PGD2 has two known receptors, GPR44 and PTGDR. GPR44 was found to be necessary for the decrease in hair growth by PGD2. This creates an exciting opportunity to perhaps create novel treatments for AGA, which inhibit the activity of PTGDS, PGD2 or GPR44. This review discusses the current knowledge surrounding PGD2, and future steps needed to translate these findings into novel therapies for patients with AGA.

Fin seit 2009 (1.25mg/Woche); Minox seit 2011; Ket seit 2012 (1%/Tag)
Abgesetzt: Dut 2011-2017 (0.05mg/Woche); RU 2014-2017 (3%/Tag)

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Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: vmPFC am Mo., 17 August 2015 10:47

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: egal123 am Mo., 17 August 2015 12:22

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: pilos am Mo., 17 August 2015 13:08

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: egal123 am Mo., 17 August 2015 13:12

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: vmPFC am Mo., 17 August 2015 12:40

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: egal123 am Mo., 17 August 2015 13:05

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: vmPFC am Mo., 17 August 2015 13:20

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: Norwood-packt-das-an am Di., 18 August 2015 23:32

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: OhNoHair am Mi., 19 August 2015 10:58

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: benutzer81 am Mi., 19 August 2015 11:24

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: Ls0701 am Mi., 19 August 2015 15:34

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: Norwood-packt-das-an am Mi., 19 August 2015 21:08

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: krx am Mi., 19 August 2015 21:54

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: imotski888 am Mi., 19 August 2015 00:34

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: BacktotheDays am Mi., 19 August 2015 17:22

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: imotski888 am Mi., 19 August 2015 18:42

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: JoBr am Mi., 19 August 2015 21:46

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: imotski888 am Mi., 19 August 2015 21:50

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: JoBr am Mi., 19 August 2015 22:01

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: imotski888 am Mi., 19 August 2015 22:03

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: Haar_Challange_2021 am So., 30 August 2015 10:55

Aw: Nieves & Garza (2014). Does prostaglandin D2 hold the cure to male pattern baldness

Von: newbie123 am Mo., 31 August 2015 12:58

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(Paper bzgl. Prostaglandine und AGA)