Haarausfall - Allgemeines Forum : Finasterid / Dutasterid » für die dut-user: zur info o. kritik: dut-aloe-gel...

für die dut-user: zur info o. kritik: dut-aloe-gel... [Beitrag #29427] :: Sa., 17 Juni 2006 17:33

habe eher zufällig bei den amis einen post zu einem dutasteride-topical mit aloe-gel gefunden, das geistert gerade durch einige foren, wie es scheint, aufgrund eines buches von einem schweizer namens michael kirsch, ein poster von hairlosshelp hat ihn ausfindig gemacht, und demnach war er Norwood 3A-4, nach einem Jahr Anwendung des Aloe-Dut-Gels Norwood 2 u. nach fast 2 Jahren Norwood 0, angeblich.

hier ein thread:
http://www.regrowth.com/hair_loss_forums/viewthread.cfm?f=1& amp; amp; amp; amp; amp; amp; amp; amp;t=16832#65034

u. ein update zu dem thema:
http://www.regrowth.com/hair_loss_forums/viewthread.cfm?f=1& amp; amp; amp; amp; amp; amp; amp; amp;t=17177#68680

in den ersten thread steht einiges dazu, worauf sich auch pilos' diagramm aus dem wiki bezieht... rel. interessantes zitiere ich mal:

"The author points out that one of the strengths of Avodart is the durability of the molecule itself. It remains very stable in the presence of other chemicals (which is why its half life in the human body is over 230 hours), so I suspect that 100 percent pure aloe gel or something less will probably not really matter. The author also found a list of items that Glaxo had listed as potential mediums for transferring the drug topically, and the list included aloe gel.

The durability of the dutasteride molecule brings up another interesting aspect that you might all want to consider as well. I read an exchange between a group of doctors and questioners on another hair loss web site in which the patients were directly challenging the doctors as to whether there was really a need to use Avodart every day since the half life was 230+ hours. That meant the drug was really going to be there doing it's job for about 3 weeks, and that it would far less expensive to take Avodart maybe only every few days or once per week and still get the same results. The doctors at first rejected this idea with a brush-off kind of answer, but after some of the questioners told them they were full of crap the doctors recanted and suggested that users could go with a lower dosage each day. After further ridicule the doctors finally gave in and agreed with the conclusion, and even made a specific statement that scientifically speaking, one Avodart every 4 days would in fact produce the same results due to the extremely long half-life, and it would be a lot less expensive for the users.

Of course there were follow-up comments that this is probably why Glaxo halted the tests for Avodart as a hair loss drug, since people would discover they could take far less of this super-durable drug and get better results than with Propecia (with its half life of only 6 hours), which Glaxo is currently selling for about $2/day per user. So releasing Avodart as an official hair loss drug would potentially create a substantial loss of recurring revenue for the company. In other words, their new drug is too good."

ob das mit diesem gel. funktioniert - weiß ich nicht. dut. ist ja wohl nicht wasserlöslich - wie also ginge das mit einem gel bezgl. penetration? aber bin eher an topicals als an oralen knallern interessiert, darum auch dieser post...

edit: dies ist das buch, von dem in den threads die rede ist:
http://www.realbooks.net/catalog/product_info.php?products_i d=187&osCsid=20bb5593ae8e3d73bd51be9711845a77

[Aktualisiert am: Sa., 17 Juni 2006 18:32]