Millionen betroffen

Haarausfall (Alopezie) bleibt rätselhaft. Anlagebedingter Haarausfall, Alopecia Areata und diffuse Alopezie (bei Frauen) sind am häufigsten.

Haarausfall  [200x250]
Oft unwirksam?

Medizinisch bedeutsam gegen Alopezie sind Propecia (Finasterid), antiandrogene Hormone bei Frauen, Regaine (Minoxidil)

Mittel gegen Haarausfall  [200x250]
Haarverpflanzung - schnelle Option

Mit einer Haarverpflanzung können die Folgen von Haarausfall schnell korrigiert werden. Techniken wie die FUE haben große Fortschritte gebracht. Eine gute Planung ist entscheidend.

Haartransplantation [200x250]


  • Androgen-Receptor-Blocker

    Fluridil, Spironolactone and Cyproterone which show a binding to the Androgen Receptor as a common activity. Anyhow they differ very much in their use and target groups (male / female)

    DHT binding to the Androgen Receptor of hair follicles is the type of treatment used for male pattern of hair loss. This includes the prevention of DHT getting created and forms it getting bound to the receptor.


    An alternative form of treatment is Fluridil, which blocks the activity of Androgen Receptor itself. The Czech Republic has approved Fluridil, and is now being used for cosmetic uses; while its marketing approval to numerous other countries has been kept pending.

    Fluridil is basically a topical ant androgen that suppresses the human androgen receptor. It is highly hydrophobic, hydrolytically degradable nonresorbable. When tried on animals, it has been proven that fluridil shows high local and general tolerance. So to find out the safety and the efficiency of fluridil in male androgentic alopecia, several tests were conducted.

    In these tests, 20 men were tested for 21 days with forearm patches of 2, 4 and 6% of fluridil, isopropanol and Vaseline. 43 men with androgentic alopecia, Norwood grade II-Va, 2% fluridil was measured in a placebo-controlled, double blind stuffy after 3 months with phototrichograms, hematology and blood chemistry. The results showed that neither fluridil nor isopropanol had any sensitization or irritation potential, unlike Vaseline. All AGA subjects showed equal anagen/telogen counts. Even after 3 months, the anagen percentage did not change in the placebo subjects; but showed an increase in fluridil subjects. There was a further increase after 9 months. 

    The first placebo subjects registered an increase in the anagen percentage after 6 months of treatment. Moreover, libido, hematology, sexual functions and blood chemistry values were the same throughout the tests. However at 3 months, during spring, serum testotestorne increased in both the placebo and fluridil groups. There was no fluridil or its decomposition product, BP-34, in the serum after 3 or 90 days. 

    With all these tests, one can come to the conclusion that topical fluridil is nonirritating, nonresorbable, no sensitizing, anagen promoting and has no systemic activity with daily use in most AGA males.


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